The Second Council of Constantinople anathematized the literal historical approach of interpreting Scripture associated with the School of Antioch as the breeder of heresy, while the council embraced allegory as the proper method of interpretation. This article looks at the historical account of these events. The author condemns the works of Theodore of Mopsuestia, but does show that the grammatical-historical approach can be linked with his method and is not the breeder of heresy but rather the defender of it. He states that the church acted wrongly in condemning this method.